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Hong Xie, Ph.D.
Assistant Research Professor
Recent Publications
1. Xie H, Wise S and Wise JP, Sr. Deficient Repair of Particulate Hexavalent Chromium-Induced DNA Double Strand Breaks Leads To Neoplastic Transformation. Mutat Res, In Press
2. Xie H, Holmes AL, Wise SS, Huang S, Peng C, Wise JP Sr. Neoplastic transformation of human bronchial cells by lead chromate particles. Am J Respir Cell Mol Biol. 2007 Nov;37(5):544-552.
3. Wise, SS, Holmes, AL, Xie, H, Thompson, WD, and Wise, Sr. JP (2006) Chronic exposure to particulate chromate induces spindle assembly checkpoint bypass in human lung cells. Chem Res Toxicol 19(11):1492-1498.
4. Xie H, Wise SS, Holmes AL, Xu B, Wakeman T, Pelsue SC, Singh NP, Wise JP,Sr. Carcinogenic lead chromate induces DNA double-strand breaks and activates ATM kinase in human lung cells. Mutat Res 2005;586(2):160-172.
5. Holmes AL, Wise SS, Xie H, Gordon N, Thompson WD, Wise JP, Sr. Lead ions do not cause human lung cells to escape chromate-induced cytotoxicity. Toxicol Appl Pharmacol 2005;203:167-176.
6. Wise SS, Holmes AL, Moreland JA, Xie H, Sandwick SJ, Stackpole MM, Fomchenko E, Teufack S, May AJ, Jr., Katsifis SP, Wise JP., Sr., Human lung cell growth is not stimulated by lead ions after lead chromate-induced genotoxicity. Mol Cell Biochem 2005;279(1-2):75-84.
7. Xie H, Holmes AL, Wise SS, Gordon N, Wise JP, Sr. Lead chromate-induced chromosome damage requires extracellular dissolution to liberate chromium ions but does not require particle internalization or intracellular dissolution. Chem Res Toxicol 2004;17:1362-1367.
8. Zhang Y, Wise JP, Holford TR, Xie H, Boyle P, Zahm SH, Rusiecki J, Zou K, Zhang B, Zhu Y, Owens PH, Zheng T. Serum polychlorinated biphenyls, cytochrome P-450 1A1 polymorphisms, and risk of breast cancer in Connecticut women. Am J Epidemiol 2004;160(12):1177-83.
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