Wise Laboratory Researching human and marine animal environmental health National Marine Cell Line Library

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Our Mission

The Wise Laboratory of Environmental and Genetic Toxicology conducts state-of-the-art research aimed at understanding how environmental toxicants affect the health of humans and marine animals.

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This mission is accomplished through the pursuit of the following general objectives:

  • Conduct innovative and multidisciplinary research in toxicology and molecular epidemiology to further our understanding of disease in humans and marine organisms, particularly as they relate to cancer, asthma and reproductive/developmental effects.
  • Discover the mechanisms used by metals to turn normal cells into tumor cells, particularly as they relate to genomic instability and DNA repair.
  • Establish new cell culture models from lung, skin, testis and ovary to investigate how metals and particulates cause cancer, asthma and reproductive/developmental effects in humans and marine organisms.
  • Study and compare contaminant-induced DNA damage and repair in models of humans and marine organisms.
  • Determine how environmental contaminant exposure may affect the recovery of critically endangered species including marine mammals, turtles and birds.
  • Investigate how marine pollution may impact the health of marine invertebrates such as lobsters, oysters, and corals.
  • Create a national resource and repository of marine cell lines and tissues.