University of Southern Maine

W. Douglas Thompson, Ph.D.
Professor of Epidemiology

Wise SS, Thompson WD, Aboueissa AM, Mason MD, Wise, JP Sr.   Particulate depleted uranium is cytotoxic and clastogenic to human lung cells.   Chemical Research in Toxicology, in press.

Thompson WD, Wartenberg D.   Additive versus multiplicative models in ecologic regression.   Stochastic Environmental Research and Risk Assessment, in press.

Wise SS, Holmes AL, Sandwick SJ, Thompson WD, Wise JP Sr.   Chronic exposure to lead chromate induces mitotic disruption and chromosome instability.   Chemical Research in Toxicology, in press.

Savery LC, Grlickova-Duzevik E, Wise SS, Thompson WD, Hinz JM, Thompson LH, Wise JP Sr.   Role of the Fanc-g gene in protecting cells from particulate chromate-induced chromosome instability.   Mutation Research, 2007;626:120-127.

Wise SS, Holmes AL, Xie H, Thompson WD, Wise JP Sr.   Chronic exposure to particulate chromate induces spindle assembly checkpoint bypass in human lung sells.   Chemical Research in Toxicology 2006;19:1492-1498.

Grlickova-Duzevik E, Wise SS, Munroe RC, Thompson WD, Wise JP Sr.   XRCC1 protects cells from chromate-induced chromosome damage, but does not affect cytotoxicity.   Mutation Research 2006;610:31-37.

Holmes AL, Wise SS, Sandwick SJ, Lingle WL, Negron VC, Thompson WD, Wise JP Sr.   Chronic exposure to lead chromate causes centrosome abnormalities and aneuploidy in human lung cells.   Cancer Research 2006;66:4041-4048.

Grlickova-Duzevik E, Wise SS, Munroe RC, Thompson WD, Wise JP Sr.   XRCC1 protects against particulate chromate-induced chromosome damage and cytotoxicity in Chinese hamster ovary cells.   Toxicological Sciences 2006;92:409-415.

Wise JP Sr, Goertz CEC, Wise SS, Morin AT, Dunn JL, Gulland FMD, Bozza M, Atkinson S, Thompson WD.   Chromium cytotoxicity in steller sea lion lung, skin and testes sells.   In Trites AW, Atkinson SK, DeMaster DP, Fritz LW, Gelatt TS, Rea LD, Wynne KM (Eds), Sea Lions of the World: Conservation and Research in the 21st Century.   Alaska Sea Grant College Program, 57-68, 2006.

Bernstein JL, Concannon P, Langholz B, Thompson WD, Bernstein L, Stovall M, Thomas DC; WECARE Study Collaborative Group.   Multi-center screening of mutations in the ATM gene among women with breast cancer - the WECARE Study.   Radiation Research 2005;163:698-699.

Holmes AL, Wise SS, Xie H, Gordon N, Thompson WD, Wise JP Sr.   Lead ions do not cause human lung cells to escape chromate-induced cytotoxicity.   Toxicology & Applied Pharmacology 2005;203:167-76.

Wise SS, Holmes AL, Ketterer ME, Hartsock WJ, Fomchenko E, Katsifis S, Thompson WD, Wise JP Sr.   Chromium is the proximate clastogenic species for lead chromate-induced clastogenicity in human bronchial cells.   Mutation Research 2004;560:79-89.

Bernstein JL, Langholz B, Haile RW, Bernstein L, Thomas DC, Stovall M, Malone KE, Lynch CF, Olsen JH, Anton-Culver H, Shore RE, Boice JD Jr, Berkowitz GS, Gatti RA, Teitelbaum SL, Smith SA, Rosenstein BS, Borresen-Dale AL, Concannon P, Thompson WD; WECARE Study.   Study design: evaluating gene-environment interactions in the etiology of breast cancer - the WECARE study.   Breast Cancer Research 2004;6:R199-214.

Bernstein JL, Bernstein L, Thompson WD, Lynch CF, Malone KE, Teitelbaum SL, Olsen JH, Anton-Culver H, Boice JD, Rosenstein BS, Borresen-Dale AL, Gatti RA, Concannon P, Haile RW; WECARE Study Collaborative Group.   ATM variants 7271T>G and IVS10-6T>G among women with unilateral and bilateral breast cancer.   British Journal of Cancer 2003;89:1513-1516.

Bernstein JL, Lapinski RH, Thakore SS, Doucette JT, Thompson WD.   The descriptive epidemiology of second primary breast cancer.   Epidemiology 2003;14:552-558.

Bernstein JL, Teraoka S, Haile RW, Borresen-Dale AL, Rosenstein BS, Gatti RA, Diep AT, Jansen L, Atencio DP, Olsen JH, Bernstein L, Teitelbaum SL, Thompson WD, Concannon P; WECARE Study Collaborative Group.   Designing and implementing quality control for multi-center screening of mutations in the ATM gene among women with breast cancer.   Human Mutation 2003;21:542-550.

Bernstein JL, Lapinski R, Lynch C, Holford T, Thompson WD.   Factors influencing mortality among young women with second primary breast carcinoma.   Cancer 2002;95:2051-2058.

Bernstein JL, Thompson WD, Casey G, DiCioccio RA, Whittemore AS, Diep AT, Thakore SS, Vaziri S, Xue S, Haile RW.   Comparison of techniques for the successful detection of BRCA1 mutations in fixed paraffin-embedded tissue.   Cancer Epidemiology, Biomarkers, and Prevention 2002;11:809-814.

Gammon MD, Hibshoosh H, Terry MB, Bose S, Schoenberg JB, Brinton LA, Bernstein JL, Thompson WD.   Oral contraceptive use and other risk factors in relation to HER-2/neu overexpression in breast cancer among young women.   Cancer Epidemiology, Biomarkers, and Prevention 1999;8:413-419.

Rosenblatt KA, Thomas DB, Jimenez LM, Fish B, McTiernan A, Stalsberg H, Stemhagen A, Thompson WD, Curnen MG, Satariano W, Austin DF, Greenberg RS, Key C, Kolonel LN, West DW.   The relationship between diet and breast cancer in men (United States).    Cancer Causes and Control 1999;10:107-113.

Gammon MD, Hibshoosh H, Terry MB, Bose S, Schoenberg JB, Brinton LA, Bernstein JL, Thompson WD.   Cigarette smoking and other risk factors in relation to p53 expression in breast cancer among young women.   Cancer Epidemiology, Biomarkers, and Prevention 1999;8:255-263.

Thompson WD.   Beyond the twinning effect: Invited commentary on "Levels of maternal serum alpha-fetoprotein in pregnant women and subsequent breast cancer risk."   American Journal of Epidemiology 1998;148:728-9.

Thompson WD.   Modeling temporal aspects of an exposure. (Letter).   Epidemiology 1998;9:362-363.

García-Closas M, Thompson WD, Robins JM.   Differential misclassification and the assessment of gene-environment interactions in case-control studies    American Journal of Epidemiology 1998;147:426-433.

Terry MB, Gammon MD, Ng-Mak D, Thompson WD.   p53 protein overexpression in relation to risk factors for breast cancer.   (Letter).   American Journal of Epidemiology 1998;147:511-512.

Skelton AK, Madan MP, Thompson WD, Wennberg DE.   Utilization patterns of cord blood gas analysis.   Obstetrics & Gynecology 1997;90:538-541.

Thompson WD.   Age at and time since: Modeling temporal aspects of exposure.   Epidemiology 1997;8:471-473.

Witte JS, Ursin G, Siemiatycki J, Thompson WD, Paganini-Hill A, Haile RW.   Diet and premenopausal bilateral breast cancer: a case-control study.   Breast Cancer Research and Treatment 1997;42:243-251.

Sheldon MR, Fillyaw MJ, Thompson WD.   The use and interpretation of the Friedman test in the analysis of ordinal-scale data in repeated measures designs.   Physiotherapy Research International 1996;1:221-228.

Kelsey JL, Whittemore AS, Evans AS, Thompson WD.   Methods in Observational Epidemiology.   Second Edition.   Oxford University Press, 1996.

Castellsague X, Thompson WD, Dubrow R.   Tubal sterilization and the risk of endometrial cancer.   International Journal of Cancer 1996;65:607-612.

Schwartz SM, Weiss NS, Daling JR, Gammon MD, Liff JM, Watt J, Lynch CF, Newcomb PA, Armstrong BK, Thompson WD.   Exogenous sex hormone use, correlates of endogenous hormone levels, and the incidence of histologic types of sarcoma of the uterus.   Cancer 1996;77:717-724.

Gruber SB, Thompson WD.   A population based study of endometrial cancer and familial risk in younger women.   Cancer Epidemiology, Biomarkers, and Prevention 1996;5:411-417.

Haile RW, Witte JS, Ursin G, Siemiatycki J, Bertolli J, Thompson WD, Paganini-Hill A.   A case-control study of reproductive variables, alcohol, and smoking in premenopausal bilateral breast cancer.   Breast Cancer Research and Treatment 1996;37:49-56.

Claus EB, Schildkraut JM, Thompson WD, Risch NJ.   The genetic attributable risk of breast and ovarian cancer.   Cancer 1996;77:2318-2324.

Thompson WD.   The risk of breast cancer after giving birth.   (Letter).   New England Journal of Medicine 1995;332:63.

Skoner MM, Thompson WD.   Response.   Re: "Factors associated with risk of stress urinary incontinence in women.   (Letter).   Nursing Research 1995;44:58.

Janerich DT, Thompson WD, Mineau GP.   Response.   Maternal pregnancy estrogens, breast cancer risk, and the Utah data.   (Letter).   Journal of the National Cancer Institute 1995;87:145-146.

Janerich DT, Thompson WD.   Reduced breast cancer risk with remarriage: Evidence of genetic-immune protection.   Epidemiology 1995;6:254-257.

Bernstein JL, Thompson WD, Risch N, Holford TR, Bruce D.   Family history and the probability of developing second primary breast cancer among women with first primary breast cancer.   (Abstract).   Genetic Epidemiology 1995;12:334.

Hitchcock JL, Steckevicz MJ, Thompson WD.   Screening mammography: Factors associated with adherence to recommended age/frequency guidelines.   Women's Health 1995;1:221-235.

Ursin G, Paganini-Hill A, Siemiatycki J, Thompson WD, Haile RW.   Early adult body weight, body mass index, and premenopausal breast cancer: Data from a case-control study.   Breast Cancer Research and Treatment 1995;33:75-82.

Jacobson HI, Thompson WD, Janerich DT.   The authors reply.   Re: "Multiple births and maternal risk of breast cancer."   (Letter).   American Journal of Epidemiology 1994;139:446-447.

Claus EB, Risch NJ, Thompson WD.   Autosomal dominant inheritance of early onset breast cancer: Implications for risk prediction.   Cancer 1994;73:643-651.

Thomas DB, Rosenblatt KA, Jimenez LM, McTiernan A, Stalsberg H, Stemhagen A, Thompson WD, Curnen MGM, Satariano W, Austin DF, Greenberg RS, Key C, Kolonel L, West D.   Ionizing radiation and breast cancer in men.   Cancer Causes and Control 1994;5:9-14.

Thompson WD.   Statistical analysis of case-control studies.   Epidemiologic Reviews 1994;16:33-50.

Thompson WD.   Genetic epidemiology of breast cancer.   Cancer 1994;74:279-287.

Skoner MM, Thompson WD, Caron VA.   Factors associated with risk of stress urinary incontinence in women: A case-control study.   Nursing Research 1994;43:301-306.

Janerich DT, Thompson WD, Mineau GP.   Maternal pattern of reproduction and risk of breast cancer in daughters: Results from the Utah Population Database.   Journal of the National Cancer Institute 1994;86:1634-1639.

Claus EB, Risch NJ, Thompson WD, Carter D.   Relationship between breast histopathology and a family history of breast cancer.   Cancer 1993;71:147-153.

Haile RW, Cortessis VK, Millikan R, Ingles S, Aragaki CC, Richardson L, Thompson WD, Paganini-Hill A, Sparkes RS.   A linkage analysis of D17S74 (CMM86) in 35 families with premenopausal bilateral breast cancer.   Cancer Research 1993;53:212-214.

Stalsberg H, Thomas DB, Rosenblatt KA, Jimenez LM, McTiernan A, Stemhagen A, Thompson WD, Curnen MGM, Satariano W, Austin DF, Greenberg RS, Key C, Kolonel L, West D.   Histologic types and hormone receptors in breast cancer in men: A population-based study in 282 North American men.   Cancer Causes and Control 1993;4:143-151.

Castellsague X, Thompson WD, Dubrow R.   Intrauterine contraception and the risk of endometrial cancer.   International Journal of Cancer 1993;54:911-916.

Inskip PD, Kleinerman RA, Stovall M, Cookfair DL, Hadjimichael O, Moloney WC, Monson RR, Thompson WD, Wactawski-Wende J, Wagoner JK, Boice JD.   Leukemia, lymphoma, and multiple myeloma following pelvic radiotherapy for benign disease.   Radiation Research 1993;135:108-124.

Haile RW, Cortessis VK, Ingles S, Millikan R, Diep A, Richardson L, Thompson WD, Paganini-Hill A, Sparkes RS, Gatti RA.   A linkage analysis of DRD2, a marker linked to the ataxia telagiectasia gene, in 68 families with premenopausal bilateral breast cancer.   Cancer Research 1993;53:5083-5085.

Ursin G, Paganini-Hill A, Siemiatycki J, Thompson WD, Haile RW.   Early adult body weight, body mass index, and premenopausal breast cancer: Data from a case-control study.   (Abstract).   American Journal of Epidemiology 1993;138:589.

Bernstein JL, Thompson WD, Risch N, Holford TR, Bruce D.   Survival after second primary breast cancer.   (Abstract).   American Journal of Epidemiology 1993;138:599.

Claus EB, Risch N, Thompson WD.   The calculation of breast cancer risk for women with a first degree family history of ovarian cancer.   Breast Cancer Research and Treatment 1993;28:115-120.

Claus EB, Risch NJ, Thompson WD.   The authors reply.   Re: "Age of onset as an indicator of familial risk of breast cancer."   (Letter).   American Journal of Epidemiology 1992;135:106.

Thomas DB, Jimenez LM, McTiernan A, Rosenblatt KA, Stalsberg H, Stemhagen A, Thompson WD, Curnen M, Satariano W, Austin DF, Issacson P, Greenberg RS, Key C, Kolonel L, West D.   Breast cancer in men: Risk factors with hormonal implications.   American Journal of Epidemiology 1992;135:734-748.

Gammon MD, Thompson WD.   The authors reply.   Re: "Polycystic ovaries and the risk of breast cancer."   (Letter).   American Journal of Epidemiology 1992;136:373.

Ursin G, Aragaki CC, Paganini-Hill A, Siemiatycki J, Thompson WD, Haile RW.   Oral contraceptives and premenopausal bilateral breast cancer -- a case-control study.   (Abstract).   American Journal of Epidemiology 1992;136:996.

Rosenblatt KA, Thomas DB, Jimenez LM, McTiernan A, Fish B, Stalsberg H, Stemhagen A, Thompson WD, Curnen M, Satariano W, Austin DF, Issacson P, Greenberg RS, Key C, Kolonel L, West D.   Nutrition and male breast cancer.   (Abstract).   American Journal of Epidemiology 1992;136:1000.

Bernstein JL, Thompson WD, Risch N, Holford TR.   Risk factors predicting the incidence of second primary breast cancer among women with a first primary breast cancer.   American Journal of Epidemiology 1992;136:925-936.

Bernstein JL, Thompson WD, Risch N, Holford TR.   The genetic epidemiology of second primary breast cancer.   American Journal of Epidemiology 1992;136:937-948.

Ursin G, Aragaki CC, Paganini-Hill A, Siemiatycki J, Thompson WD, Haile RW.   Oral contraceptives and premenopausal bilateral breast cancer -- a case-control study.   Epidemiology 1992;3:414-419.

Janerich DT, Thompson WD, Varela LR, Greenwald P, Chorost S, Tucci C, Zaman MB, Melamed MR, Kiely M, McKneally MF.   Lung cancer and exposure to tobacco smoke in the household.   (Letter).   New England Journal of Medicine 1991;324:414-415.

Claus EB, Risch N, Thompson WD.   Genetic analysis of breast cancer in the Cancer and Steroid Hormone Study.   American Journal of Human Genetics 1991;48:232-242.

Rosenblatt KA, Thomas DB, McTiernan A, Austin MA, Stalsberg H, Stemhagen A, Thompson WD, Curnen M, Satariano W, Austin DF, Issacson P, Greenberg RS, Key C, Kolonel L, West D.   Breast cancer in men: Aspects of familial aggregation.   Journal of the National Cancer Institute 1991;83:849-854.

Demers PA, Thomas DB, Rosenblatt KA, Jimenez LM, McTiernan A, Stalsberg H, Stemhagen A, Thompson WD, Curnen M, Satariano W, Austin DF, Issacson P, Greenberg RS, Key C, Kolonel L, West D.   Occupational exposure to electromagnetic fields and breast cancer in men.   American Journal of Epidemiology 1991;134:340-347.

Schwartz SM, Weiss NS, Daling JR, Newcomb PA, Liff JM, Gammon MD, Thompson WD, Watt JD, Armstrong BK, Weyer P, Isaacson P, Ek M.   Incidence of histologic types of uterine sarcoma in relation to menstrual and reproductive history.   International Journal of Cancer 1991;49:362-367.

Gammon MD, Thompson WD.   Polycystic ovaries and the risk of breast cancer.   American Journal of Epidemiology 1991;134:818-824.

Thompson WD, Schildkraut JM.   Family history of gynecologic cancers: Relationships to the incidence of breast cancer prior to age 55.   International Journal of Epidemiology 1991;20:595-602.

Thompson WD.   Effect modification and the limits of biological inference from epidemiologic data.   Journal of Clinical Epidemiology 1991;42:221-232.

Claus EB, Risch NJ, Thompson WD.   Age of onset as an indicator of familial risk of breast cancer.   American Journal of Epidemiology 1990;131:961-972.

Claus EB, Risch NJ, Thompson WD.   Using age of onset to distinguish between subforms of breast cancer.   Annals of Human Genetics 1990;54:169-177.

Janerich DT, Mayne ST, Thompson WD, Stark AD, Fitzgerald EF, Jacobson HI.   Familial clustering of neural tube defects and gastric cancer.   International Journal of Epidemiology 1990;19:516-521.

Jacobson HI, Thompson WD, Janerich DT.   The authors reply. Re: "Multiple births and maternal risk of breast cancer." (Letter).   American Journal of Epidemiology 1990;132:201.

Demers PA, Thomas DB, Rosenblatt KA, Jimenez LM, McTiernan A, Stalsberg H, Stemhagen A, Thompson WD, Curnen M, Satariano A, Austin DF, Isacson P, Greenberg RS, Key C, Kolonel L, West D.   Occupational exposure to electromagnetic radiation and breast cancer in males. (Abstract).   American Journal of Epidemiology 1990;132:775-776.

Rosenblatt KA, Thomas DB, Jimenez LM, McTiernan A, Stalsberg H, Stemhagen A, Thompson WD, Curnen M, Satariano A, Austin DF, Isacson P, Greenberg RS, Key C, Kolonel L, West D.   Exposure to ionizing radiation and breast cancer in men. (Abstract).   American Journal of Epidemiology 1990;132:776.

Gammon MD, Thompson WD.   Polycystic ovaries and the risk of breast cancer. (Abstract).   American Journal of Epidemiology 1990;132:767-768.

Thompson WD.   Assessing etiologic heterogeneity. (Abstract).   American Journal of Epidemiology 1990;132:780.

Gammon MD, Thompson WD.   Infertility and breast cancer: A population-based case-control study.   American Journal of Epidemiology 1990;32:708-716.

Thompson WD.   Nonrandom yet unbiased.   Epidemiology 1990;1:262-265.

Janerich DT, Thompson WD, Varela LR, Greenwald P, Chorost S, Tucci C, Zaman MB, Melamed MR, Kiely M, McKneally MF.   Lung cancer and exposure to tobacco smoke in the household.   New England Journal of Medicine 1990;323:632-636.

Thompson WD.   Kappa and attenuation of the odds ratio.   Epidemiology 1990;1:357-369.